Abstract: Background: A neuropsychiatric condition with an unclear etiology is schizophrenia. Inflammation, infection, and genetic variables have all been found to contribute to the etiology of disease. The present study was conducted to assess cardiovascular disease risk in schizophrenia patients.

Materials & Methods: 48 patients of Schizophrenia diagnosed by DSM-IV criteriawere put in group I and controls in group II. Height (in metres) and weight (in kgs), BMI= Weight/(Height)2, waist circumference, blood pressure, fasting plasma glucose, serum lipid parameters and hs-CRP were measured.

Results: Group I had 22 males and 26 females and group II had 24 males and 24 females. In group I and group II, mean BMI was 28.3 and 27.5, waist circumference was 89.2 and 82.1, triglycerides was 119.8 and 97.5, HDL was 37.8 and 41.2, SBP was 126.5 and 120.3, DBP was 82.5 and 79.2, fasting glucose was 94.5 and 88.3, metabolic syndrome was seen in 14 and 4, total cholesterol was 152.6 and 142.8, LDL was 120.8 and 114.3, laboratory dyslipidemia was seen in 24 and 5 respectively. The difference was significant (P< 0.05).

Conclusion: Due to the high frequency of metabolic syndrome and dyslipidemia, individuals with schizophrenia are more likely to experience cardiovascular disease events. These patients should have their CVD risk factors routinely checked, and they should be promptly referred to a doctor for additional care.