Background: Vaginal infections are common among women of reproductive age. They can be caused by sexually transmitted microorganisms or by some disorder resulting in the proliferation of endogenous microbiota. Among the more frequent microorganisms are the protozoan Trichomonas vaginalis (T. vaginalis) and Candida albicans (C. albicans). Aim of this study to find out the Prevalence of Trichomonas vaginalis & Candidia species (primary) and socio-demographic profile and different clinical presentations (secondary) in women of Reproductive Age Group with vaginal discharge. Methods: Total 140 sexually active females age group of 18- 45 yrs with meeting the eliglibility criteria complain of vaginal discharge. High vaginal swabs (HVS) were collected from the patients and processed for microscopy and culture. Comparative study was done by using chi-square test. Result: The prevalence of Candida species and Trichomonas vaginalis is calculated to be 27.8% and 4.3% respectively. Total 67% belong to rural population in candiasis where 83% belong to urban population in Trichomoniasis. Maximum number (77%) in Candiasis and all cases (100%) in Trichomoniasis were belonging to low socio economic status. Multiparous women were more prone for both candiasis and trichomoniasis infection. In both infections, majority were using OCP as contraceptive measure. Total 43%patients were having symptoms of vaginal discharge + pruritus + dysuria in candiasis and 66% patients were having vaginal discharge only in Trichomoniasis. Around 54% of total candidiasis was Diabetic which is highly significant. Conclusion: The prevalence of Candiasis and Trichomoniasis in my study is 27.8% and 4.3% respectively. Diabetes mellitus is imposed as a major risk factor for Candida species infection.